There is a Hole in the Universe

"It is not like a hole in the wall where a mouse slips through, solid and crisp and leading from somewhere to someplace.  It is rather like a hole in the heart, an amorphous and edgless void.  It is a heartfelt absence, a blank space where something is missing, a large and oblivious blind spot in our understanding of the universe.

That missing something, strange to say, is a grasp of nothing itself.  Understanding nothing matters, because nothing is the all-important background upon which everything else happens."

K.C. Cole, The Hold in the Universe:  How Scientists Peered over the Edge of Emptiness and Found Everything

http://www.amazon.com/gp/reader/015100398X/ref=sib_dp_pt#reader-link